A Histidine Was Determined to Be the Critical Residue Involved

question 44

Multiple Choice

A histidine was determined to be the critical residue involved in an enzyme-catalyzed reaction. If the pK_a of the histidine is known to be 6.5 in the active site and the pH of maximum catalytic activity is 7.2, what is likely the primary role of histidine in the catalytic reaction?

• A) acts as a proton donor
• B) forms a covalent bond with the substrate
• C) stabilizes a charged intermediate
• D) reduces the entropy of the substrate

---

Definitions:

Prior Period

A previous accounting time frame used for comparison purposes or to correct errors in financial statements.

Same Industry

Refers to companies and businesses that operate within the same sector or category, offering similar products or services.

Peculiar Conditions

Unique or unusual circumstances that can affect an outcome or situation in specific cases.

General Economic Conditions

The overall state of the economy, including factors like inflation rates, unemployment levels, and GDP growth.