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Aspartate and Lysine Are in the Active Site of an Enzyme

question 68

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Aspartate and lysine are in the active site of an enzyme. They are both known to participate directly in catalysis. The pKaʹs of the residues are found to be 3.2 and 9.6, respectively for aspartate and lysine. The optimum pH for the enzyme is 6.4. Which forms of these two residues will predominate when the enzyme is most active?


Definitions:

Reinforce Behaviour

The process of encouraging or establishing a pattern of behavior by offering rewards or consequences.

Negative Reinforcement

A behavioral psychology principle where the removal of an unpleasant stimulus following a desired behavior increases the likelihood of that behavior being repeated in the future.

Punishment

A consequence that reduces the likelihood of a behavior being repeated, often used in behavioral conditioning.

Positive Reinforcement

A technique in behaviorism that encourages a certain behavior by following it with a positive stimulus or reward.

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