Which of the Following S_N2 Reactions Is the Slowest B)

question 62

Multiple Choice

Which of the following S_N2 reactions is the slowest?

• A) \(\mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 3 } \mathrm { Br } + \mathrm { HO } ^ { - } \rightarrow \mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 3 } \mathrm { OH } + \mathrm { Br } ^ { - }\)
• B) \(\mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 2 } \mathrm { Cl } + \mathrm { HO } ^ { - } \rightarrow \mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 2 } \mathrm { OH } + \mathrm { Cl } ^ { - }\)
• C) \(\mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 2 } \mathrm { I } + \mathrm { HO } ^ { - } \rightarrow \mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 2 } \mathrm { OH } + \mathrm { I } ^ { - }\)
• D) \(\mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 3 } \mathrm {~F} + \mathrm { HO } ^ { - } \rightarrow \mathrm { CH } _ { 3 } \mathrm { CH } _ { 2 } \mathrm { CH } _ { 2 } \mathrm { OH } + \mathrm { F } ^ { - }\)

Explain the synthesis and reactions of amines, including selective preparation strategies.

Understand the principles of stereochemistry in relation to the synthesis of chiral amine compounds.

Relate the structure of organic compounds to their potential biomedical applications.

Illustrate detailed reaction mechanisms for nucleophilic substitutions and eliminations.

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