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Use the given transformation to evaluate the integral.
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where is the parallelogram bounded by the lines
Tolerance
The body's reduced response to a drug after prolonged use, requiring an increased dosage to achieve the original effect.
Illicit Substance
A substance whose production, sale, or use is prohibited by law.
Bioavailability
The degree and rate at which a drug or other substance is absorbed or becomes available at the intended biological site of action.
Older Adults
A demographic group generally defined as individuals aged 65 years and older, often considered in the context of healthcare, social services, and epidemiological studies.
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