The Reaction Below Is a Direct Enolate Alkylation

question 27

Multiple Choice

The reaction below is a direct enolate alkylation.It has been found that this reaction only works well with unhindered methyl and 1° alkyl halides.Pick the statement that best explains this observation.

• A)The nucleophilic enolate requires a reaction center that has a positive charge.
• B)Hindered alkyl halides do not undergo S_N1 reactions.
• C)Hindered alkyl halides do not undergo S_N2 reactions.
• D)Methyl and 1° alkyl halides can form carbocations that can readily react with the nucleophilic enolate.

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Definitions:

Posterior Probabilities

Probabilities that are updated based on new evidence or information, typically used in Bayesian statistics.

Prior Probabilities

Probabilities that reflect beliefs about the uncertainty of events before new evidence is considered.

Likelihood Probabilities

Measures of the plausibility of a hypothesis given certain data, not necessarily summed to one.

Posterior Probabilities

Probabilities that are updated as more evidence or information becomes available, commonly used in Bayesian statistics.