Chimeric Antigen Receptors (CARs)have Evolved in Molecular Structure Through Three

question 22

Multiple Choice

Chimeric antigen receptors (CARs) have evolved in molecular structure through three generations of design. Which of the following statements regarding the three generations of CARs is correct?

• A)the first generation CARs were the largest most complex molecules
• B)the second generation CARs possessed two VH and two VL domains
• C)the third generation CARs possessed the most costimulatory domains
• D)the third generation CARs possessed three VH and two VL domains

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Definitions:

Negative Correlation

A relationship between two variables in which one variable increases as the other decreases, and vice versa.

Positive Correlation

A relationship between two variables where they move in the same direction, indicating that as one variable increases, so does the other.

Criterion-related Validity

The extent to which a test successfully measures an operational variable and can predict a criterion or outcome.

Validity

The extent to which a test, measurement, or research accurately reflects or assesses the specific concept it is intended to measure.