Chimeric Antigen Receptors (CARs)have Evolved in Molecular Structure Through Three

question 22

Multiple Choice

Chimeric antigen receptors (CARs) have evolved in molecular structure through three generations of design. Which of the following statements regarding the three generations of CARs is correct?

• A)the first generation CARs were the largest most complex molecules
• B)the second generation CARs possessed two VH and two VL domains
• C)the third generation CARs possessed the most costimulatory domains
• D)the third generation CARs possessed three VH and two VL domains

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Definitions:

Transcranial Magnetic Stimulation (TMS)

A non-invasive procedure that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression and other conditions.

Electrocardiograph (ECG)

A medical device used to record the electrical activity of the heart over a period of time.

Electrical Stimulation of the Brain (ESB)

A neuroscientific technique used to elicit a reaction from the brain by applying a controlled amount of electrical current to specific areas of the brain.

Meninges

The three layers of protective membranes—dura mater, arachnoid mater, and pia mater—surrounding the brain and spinal cord.