You Are Working with Adult Mouse Fibroblast Cells

question 86

Multiple Choice

You are working with adult mouse fibroblast cells. The genes for transcription factors from pluripotent stem cells are transduced into the adult fibroblast cells as part of viral vectors in various combinations, and once inside the cells they are expressed. What results would you expect to obtain? (Select all correct choices)

• A)The fibroblasts die.
• B)A combination of transduced genes for only four specific transcription factors is sufficient to reprogram the fibroblasts into undifferentiated cells.
• C)A combination of transduced genes for only four specific transcription factors is sufficient to cause the fibroblasts to behave like pluripotent ES cells.
• D)A combination of transduced genes for only four specific transcription factors is sufficient to cause a terminal differentiation of the fibroblast cells.

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Definitions:

Split-off

A point in the production process in a joint production system where two or more products become individually identifiable and their costs can be separately allocated.

Production Work

The tasks and activities involved in manufacturing products, including assembly and processing materials.

Assembly Line

A manufacturing process in which parts are added to a product in a sequential manner to create a finished product efficiently.

Joint Costs

Costs that are incurred in the process of producing two or more products simultaneously up to the point where these products are separable.