The Reverse Reaction of Nucleic Acid Synthesis Almost Never Happens

question 73

Multiple Choice

The reverse reaction of nucleic acid synthesis almost never happens. What prevents it?

• A)The enzyme does not work in reverse.
• B)Polynucleotides are too stable to depolymerize.
• C)H bonds holding the strands together are too strong.
• D)Nucleic acid synthesis is coupled to the highly exergonic pyrophosphate hydrolysis.
• E)There is a large uptake of free energy.

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