Bardet‐Biedl Syndrome (BBS)is Caused by Mutations in Any One of a Number

question 45

Multiple Choice

Bardet‐Biedl syndrome (BBS) is caused by mutations in any one of a number of genes that affect protein trafficking into cilia. Persons afflicted with BBS exhibit a remarkable range of abnormalities, like polydactyly, obesity, kidney disease, etc. These disparatesymptoms are thought to reflect the function of cilia ________________.

• A)as sensors for a magnetic field
• B)aslocomotory organelles
• C)as sources of flagella
• D)as binding sites for actin
• E)as antennas to receive signals that regulate development and physiology