Why Does Targeting Glucocerebrosidase to Lysosomes in Macrophages Serve as a Treatment

question 141

Multiple Choice

Why does targeting glucocerebrosidase to lysosomes in macrophages serve as a treatment for Gaucher's disease?

• A)Glucocerebrosidase is normally denatured in the lysosomes.
• B)Glucocerebrosidase is delivered to the precise sites in the cell where the deficiency is manifested, correcting the deficit.
• C)Glucocerebrosidase denatures the cytoplasm from its location in the lysosomes, correcting the deficit.
• D)Glucocerebrosidase binds to the outer lysosome surface and breaks down glycogen in the cytoplasm.
• E)Glucocerbrosidase is supposed to digest most of the enzymes in the lysosome.

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