Normal Hemoglobin Is a Tetramer, Consisting of Two Molecules of β

question 58

Multiple Choice

Normal hemoglobin is a tetramer, consisting of two molecules of β hemoglobin and two molecules of α hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits

• A) altered primary structure.
• B) altered secondary structure.
• C) altered tertiary structure.
• D) altered quaternary structure.
• E) altered primary structure and altered quaternary structure; the secondary and tertiary structures may or may not be altered.

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Definitions:

Well-Being

The state of experiencing health, happiness, and prosperity, encompassing physical, mental, and emotional health.

Coronary Heart Disease

A condition characterized by decreased blood flow to the heart muscle, often resulting in chest pain or heart attack.

Cardiac Rehabilitation

A medically supervised program designed to improve cardiovascular health following a heart attack, heart failure, or surgery.

Symptoms

are signs or indicators of a condition or disease, often providing clues to the presence of a health issue, which may be physical or psychological.