In the Presence of Oxygen, the Three-Carbon Compound Pyruvate Can

question 98

Multiple Choice

In the presence of oxygen, the three-carbon compound pyruvate can be catabolized in the citric acid cycle. First, however, the pyruvate (1) loses a carbon, which is given off as a molecule of CO₂, (2) is oxidized to form a two-carbon compound called acetate, and (3) is bonded to coenzyme A.
-Why is coenzyme A, a sulfur-containing molecule derived from a B vitamin, added?

• A) because sulfur is needed for the molecule to enter the mitochondrion
• B) in order to utilize this portion of a B vitamin which would otherwise be a waste product from another pathway
• C) to provide a relatively unstable molecule whose acetyl portion can be readily transferred to a compound in the citric acid cycle
• D) because it drives the reaction that regenerates NAD⁺
• E) in order to remove one molecule of CO₂

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