Abnormal Chromosomes Are Frequently Found in Malignant Tumors

question 47

Multiple Choice

Abnormal chromosomes are frequently found in malignant tumors. Errors such as translocations may place a gene in close proximity to different control regions. Which of the following might then occur to make the cancer worse?

• A) an increase in nondisjunction
• B) expression of inappropriate gene products
• C) a decrease in mitotic frequency
• D) death of the cancer cells in the tumor
• E) sensitivity of the immune system

---

Definitions:

Span of Control

The number of individuals or resources one manager or leader directly supervises or oversees.

Formalization

The extent to which an organization's policies, procedures, job descriptions, and rules are written and explicitly articulated.

Creativity

The ability to produce original and valuable ideas or solutions.

Centralization

The degree to which decisions are made at the top of the organization.