Genomic Imprinting Is Generally Due to the Addition of Methyl

question 17

Multiple Choice

Genomic imprinting is generally due to the addition of methyl (-CH₃) groups to C nucleotides in order to silence a given gene. If this depends on the sex of the parent who transmits the gene, which of the following must be true?

• A) Methylation of C is permanent in a gene.
• B) Genes required for early development stages must not be imprinted.
• C) Methylation of this kind must occur more in males than in females.
• D) Methylation must be reversible in ovarian and testicular cells.
• E) The imprints are transmitted only to gamete-producing cells.

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