Which of the Following Mutations Is Most Likely to Cause

question 27

Multiple Choice

Which of the following mutations is most likely to cause a phenotypic change?

• A) a duplication of all or most introns
• B) a large inversion whose ends are each in intergenic regions
• C) a nucleotide substitution in an exon coding for a transmembrane domain
• D) a single nucleotide deletion in an exon coding for an active site
• E) a frameshift mutation one codon away from the 3' end of the nontemplate strand

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