Use the Following Information as Background for the Next Few

question 38

Multiple Choice

Use the following information as background for the next few questions.
Immunodeficiencies can be genetic in origin, and two examples are Bruton's agammaglobulinemia, an X-linked disorder, and DiGeorge syndrome, caused by a deletion from chromosome 22. Bruton's disorder results in underdeveloped B cells, whereas DiGeorge syndrome results in a missing or seriously underdeveloped thymus.
-Bruton's disorder will likely include

• A) the failure of heavy-chain gene rearrangement in B cells.
• B) the failure to incorporate CD4 receptors into cell membranes.
• C) an underexpression of the gene for the β chain of the T cell receptor.
• D) an underexpression of the gene for the CD8 receptor molecule.
• E) the inability of the bone marrow cells to interact with MHC molecules.

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