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X-Linked Hyper IgM Syndrome (XHIM) Is an Immunodeficiency Disorder Caused

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X-linked hyper IgM syndrome (XHIM) is an immunodeficiency disorder caused by mutations of the gene encoding CD154. Why is this disease characterized by recurrent infections (starting in childhood) and elevated serum levels of IgM?


Definitions:

Colonization

The process by which a central power dominates the surrounding land and its indigenous people, often involving the establishment of foreign control over territories for economic or strategic benefits.

South Carolina

A state in the southeastern region of the United States, known for its shoreline of subtropical beaches and marshlike sea islands, as well as its rich history in the American Civil War.

Colony Formation

The process by which countries establish settlements in distant territories under their control, often for economic gain, strategic advantage, or to spread their cultural or religious beliefs.

Colonial Development

The process by which European powers established and expanded colonies overseas, often involving the exploitation of local resources and indigenous populations.

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