First Attempts to Develop Cholesterol-Lowering Drugs Targeted the Later Steps

question 4

Multiple Choice

First attempts to develop cholesterol-lowering drugs targeted the later steps in cholesterol biosynthesis. Why did this strategy have to be abandoned?

• A) These reactions were so efficient that they could not be blocked.
• B) The accumulation of an insoluble substrate caused cataracts and other deleterious side effects.
• C) All of the drugs that were developed actually enhanced cholesterol synthesis.
• D) None of the drugs that were developed could survive the acid conditions in the stomach.
• E) These drugs caused untreatable gall stones.

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Definitions:

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An upward adjustment in prices, charges, or interest rates, typically within a business or economic context.

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A costing method used in manufacturing where costs are assigned to a product based on the process it goes through in the production cycle.

Variable Cost

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