The Mechanism by Which Type I Topoisomerase Relaxes DNA Includes

question 43

Multiple Choice

The mechanism by which type I topoisomerase relaxes DNA includes which of the following?

• A) The OH of Tyr 723 attacks a phosphate group on one DNA strand.
• B) When the backbone of one strand is cleaved, the DNA rotates.
• C) ATP binds, leading to a conformation change.
• D) All the answers are correct.
• E) The OH of Tyr 723 attacks a phosphate group on one DNA strand, and when the backbone of one strand is cleaved, the DNA rotates.

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