What Clues Provided Evidence of the Mechanism of Channel Inactivation

question 13

Multiple Choice

What clues provided evidence of the mechanism of channel inactivation?

• A) Trypsin digestion of the cytoplasmic side caused the channel to stay open.
• B) Protein mutants have different inactivation kinetics.
• C) Inactivation could be restored by the addition of part of a missing peptide.
• D) A and B
• E) All of the answers are correct.

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