Changes in ATCase Conformation Were Detected by Crystallizing the Enzyme

question 7

Multiple Choice

Changes in ATCase conformation were detected by crystallizing the enzyme in the presence of PALA (N-(phosphonacetyl) -L-aspartate) . What is PALA?

• A) a radioactive tag that binds to the subunits
• B) a substrate analog that resembles the transition state
• C) a fluorescent allosteric inhibitor analog
• D) All of the answers are correct.
• E) None of the answers is correct.

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