In a Metabolic Pathway, Succinate Dehydrogenase Catalyzes the Conversion of Succinate

question 8

Multiple Choice

In a metabolic pathway, succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by malonic acid, a substance that resembles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the amount of succinate molecules to those of malonic acid reduces the inhibitory effect of malonic acid. What role does malonic acid play with respect to succinate dehydrogenase?

• A) Malonic acid is a competitive inhibitor.
• B) Malonic acid blocks the binding of fumarate.
• C) Malonic acid is a noncompetitive inhibitor.
• D) Malonic acid is an allosteric regulator.

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Definitions:

Predetermined Overhead Rate

A calculated rate used to apply manufacturing overhead to products or job orders, based on a related activity measure such as labor hours.

Variable Manufacturing Overhead

The costs that vary with production volume, such as indirect materials, utilities, and labor involved in the manufacturing process.

Machine-Hour

A measure of production output or activity based on the number of hours a machine is operated.

Fixed Manufacturing Overhead

A consistent cost incurred during manufacturing that does not vary with the level of production, such as salaries of managers or rent.