The Number of Major Histocompatibility (MHC) Protein Combinations Possible in a Given

question 15

Multiple Choice

The number of major histocompatibility (MHC) protein combinations possible in a given population is enormous. However, an individual in that diverse population has a far more limited array of MHC molecules because ________.

• A) the MHC proteins are made from several different gene regions that are capable of rearranging in a number of ways
• B) MHC proteins from one individual can only be of class I or class II
• C) each of the MHC genes has a large number of alleles, but each individual only inherits two for each gene
• D) once a B cell has matured in the bone marrow, it is limited to two MHC response categories

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