You've Forgotten What Happens After Sensitization, So Your Friend Gives

question 10

Multiple Choice

You've forgotten what happens after sensitization, so your friend gives you a summary. Which is the CORRECT statement?

• A) Complement protein C3a binds to two IgE molecules bound to the surface of the basophil, causing it to degranulate and release histamine and other mediators.
• B) On second  exposure, complement protein C3a binds to two IgG molecules attached to the surface of the mast cell, causing it to degranulate and release interleukins.
• C) On second exposure, complement protein C5b cross-links two allergen molecules bound to the surface of the basophil, causing it to degranulate and release histamine and other mediators.
• D) On second exposure, the allergen cross-links two IgE antibodies bound to the surface of the basophil, causing it to degranulate and release histamine and other mediators.
• E) Second exposure to the allergen causes activation of B cells that are initially programmed to produce IgM molecules, but then undergo class switching to produce IgE.

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