Which Statement Regarding the Pathogenesis of Necrotizing Fasciitis Is INCORRECT

question 41

Multiple Choice

Which statement regarding the pathogenesis of necrotizing fasciitis is INCORRECT?

• A) The causative agent produces SPE A, a superantigen that causes helper T cells to release large amounts of cytokines, leading to toxic shock.
• B) SPE B is a protease produced by S. pyogenes that causes tissue death and breakdown, leading to fluid accumulation in the area and intense swelling.
• C) A hyaluronic acid capsule and M protein allow the causative agent to evade the immune responses.
• D) M protein-fibrinogen complexes causes neutrophils to release inflammatory molecules that increase vascular permeability and lead to a blood pressure drop.
• E) The causative agent sheds antibodies that attach to fibrinogen and recruit natural killer cells that destroy muscle fascia through ADCC.

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