Would Babies Need to Be Immunized Against Lockjaw (Tetanus) If

question 59

Multiple Choice

Would babies need to be immunized against lockjaw (tetanus) if their mother had been immunized against the disease?  Why or why not?

• A) No, because the mother's IgG antibodies would be passed along through the placenta before birth, protecting the baby from the infection.
• B) Yes, because even though maternal IgG antibodies might be passed along through the placenta, they will not last forever. The baby will need to create its own antibody response to be protected against future tetanus.
• C) No, because maternal IgG antibodies would be passed along in the breast milk, protecting the baby from infection.
• D) Yes, because the maternal response to the tetanus vaccine is to produce IgE antibodies, and IgD antibodies are the predominant type in breast milk. Therefore, even if the baby is breast-fed, it won't receive the mother's protective antibodies.
• E) Yes, because although the mother will make IgG antibodies in response to the vaccine, these antibodies cannot cross the placenta, so the baby is not protected at all.

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