It Is Possible to Cultivate Clostridium Tetani from a Wound

question 70

Multiple Choice

It is possible to cultivate Clostridium tetani from a wound, even if the affected person does not have tetanus. How can this be explained?

• A) If Clostridium tetani is cultured from a wound, the person MUST have tetanus. However, in some people the signs and symptoms of tetanus are extremely mild, so it can be difficult to detect the disease in them.
• B) Clostridium tetani may be growing vigorously in the wound. However, the organism only produces tetanospasmin if the person's immune system is compromised, so a healthy person may not develop the disease.
• C) The wound may contain spores that can be germinated under appropriate conditions in culture. However, they will not germinate in a wound unless it is anaerobic. Since the spores themselves do not produce toxin, their presence does not lead to tetanus.
• D) Clostridium tetani is part of the normal microbiota of the integumentary, cardiovascular, and lymphatic systems. It makes sense that it would be possible to culture the organism from a wound, even in a healthy person.
• E)  None of these adequately explains how C. tetani can be cultured from the wound of a healthy person.

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