Why Is an Accurate Estimate of Gestational Age Necessary Before

question 6

Multiple Choice

Why is an accurate estimate of gestational age necessary before maternal serum α-fetoprotein (MSAFP) is measured?

• A) It is only expressed early in pregnancy
• B) It is only expressed in the second trimester of pregnancy
• C) One must relate the MSAFP measurement to gestational age because the MSAFP levels change during the pregnancy
• D) If it is too late in the pregnancy to do more invasive testing, it's not worth doing MSAFP measurements
• E) Because it takes several days to do the MSAFP testing, it can be skipped and invasive testing if the pregnancy is beyond 16 weeks can be done

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