What Is the Likely Explanation When Individuals with Cystathionine-Synthase Deficiency

question 5

Multiple Choice

What is the likely explanation when individuals with cystathionine-synthase deficiency do not respond to treatment by cofactor supplementation?

• A) They have a dominant negative mutation
• B) They have a recessive mutation
• C) They lack residual cystathionine synthase activity
• D) The level of vitamin supplementation required to stimulate their cystathionine synthase is toxic
• E) The cofactor binding site is mutated

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