Polyethylene Glycol Modification of Adenosine Deaminase for Enzyme Replacement Therapy

question 11

Multiple Choice

Polyethylene glycol modification of adenosine deaminase for enzyme replacement therapy has which of the following effects?

• A) Enhances the catalytic activity of the enzyme
• B) Reduces likelihood of eliciting a neutralizing antibody response to the protein
• C) Enhances cofactor binding of the enzyme
• D) Stabilizes the protein conformation
• E) All of the above

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