What Is the Mechanism of Decitabine Treatment for Sickle Cell

question 9

Multiple Choice

What is the mechanism of decitabine treatment for sickle cell disease?

• A) Incorporation of decitabine into DNA causes γ-globin promoter hypermethylation
• B) Incorporation of decitabine into DNA causes γ-globin promoter hypomethylation
• C) Incorporation of decitabine into RNA increases γ-globin translation
• D) Incorporation of decitabine into RNA decreases γ-globin translation
• E) Incorporation of decitabine into HbS increases its function

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