CGG Expansions in the 5' Untranslated Region 5'UTR of FMR1

question 20

Multiple Choice

CGG expansions in the 5' untranslated region 5'UTR of FMR1 cause which of the following?

• A) Expression of polyglutamine sequences
• B) Repeat methylation and transcriptional silencing
• C) Gain of function toxicity of the FMR1 mRNA
• D) A or B
• E) B or C

---

Definitions:

Long-Term Note

A debt security that matures in more than one year, requiring the borrower to repay the principal and interest over an extended period.

Financing Activities

Transactions and events that affect the long-term liabilities and equity of an organization, such as issuing stocks or bonds, and repaying bank loans.

Decrease

The act of becoming smaller or fewer in size, amount, intensity, or degree; a reduction in value or quantity.

Accounts Payable

This term refers to the amounts owed by a company to suppliers or creditors for goods and services received but not yet paid for.