What Is the Likely Mechanism by Which Repeat Expansions Cause

question 24

Multiple Choice

What is the likely mechanism by which repeat expansions cause myotonic dystrophy?

• A) Expression of polyglutamine sequences
• B) Repeat methylation and transcriptional silencing
• C) Translational silencing by the repeat
• D) Expanded repeats sequester excessive amounts of RNA-binding proteins
• E) C and D

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Definitions:

Pareto Efficient

A Pareto efficient outcome is one in which it is impossible to make any one individual better off without making at least one individual worse off, indicating an optimal allocation of resources.

Utility Function

A mathematical representation of how a consumer's preferences between different goods or services translate into levels of satisfaction or utility.

Initial Endowment

Refers to the initial allocation of goods, resources, or wealth that an individual or entity possesses before any transactions.

Pareto Efficient

A situation where no individual or preference criterion can be better off without making at least one individual or preference criterion worse off.