CGG Expansions in the 5' Untranslated Region 5'UTR of FMR1

question 20

Multiple Choice

CGG expansions in the 5' untranslated region 5'UTR of FMR1 cause which of the following?

• A) Expression of polyglutamine sequences
• B) Repeat methylation and transcriptional silencing
• C) Gain of function toxicity of the FMR1 mRNA
• D) A or B
• E) B or C

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Definitions:

Breast Cancer

A type of cancer that forms in the cells of the breasts, known for being one of the most common cancers in women worldwide.

Adaptive

Capable of adjusting to new conditions or environments, or modified for a particular use or purpose.

Developmental Stressor

An event or condition that disrupts the normal developmental process, causing stress or adjustment challenges.

Nursing Diagnoses

Clinical judgments about individual, family, or community experiences/responses to actual or potential health problems/life processes.