What Is the Most Likely Explanation for a Set of Unaffected

question 3

Multiple Choice

What is the most likely explanation for a set of unaffected parents having two children with a highly-penetrant, autosomal dominant disorder?

• A) Two new mutations occurred in the same gene
• B) Germline mosaicism in one of the parents
• C) Variable expressivity
• D) Somatic reversion in carrier parent
• E) Inactivation of mutant allele in carrier parent

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Definitions:

Productive

Having the power to produce; effectively generating goods, services, or results.

General Adaptation Syndrome

A model describing the body's short-term and long-term reactions to stress, consisting of three stages: alarm, resistance, and exhaustion.

Physiological Damage

Harm caused to the normal functions and structures of an organism's body.

Stress Management

A wide spectrum of techniques and psychotherapies aimed at controlling a person's levels of stress, especially chronic stress, for the purpose of improving everyday functioning.