Alport Syndrome, a Dominantly Inherited X-Linked Disorder, Is Characterized by Glomerulonephritis

question 29

Multiple Choice

Alport syndrome, a dominantly inherited X-linked disorder, is characterized by glomerulonephritis, end-stage kidney disease, and hearing loss. A mother with alport disease, whose father was unaffected, marries an unaffected man. What are the chances that she would give birth to a son with alport syndrome?

• A) 0%
• B) 25%
• C) 50%
• D) 75%
• E) 100%

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Definitions:

Realistic Expectations

Expectations that are founded on practical and achievable standards, acknowledging the likelihood of outcomes based on facts and evidence.

Triangular Theory

A psychological theory that conceptualizes love in terms of three components: intimacy, passion, and commitment.

Intimacy

A near, intimate, and typically warm or affectionate connection with another individual or group.

Marriage Gradient

The tendency for women to marry men who are older, taller, or socially and economically better off.