Warfarin Skin Necrosis Occurs Within the First 2 to 3

question 12

Multiple Choice

Warfarin skin necrosis occurs within the first 2 to 3 days after starting warfarin therapy because

• A)the platelet count decreases to fewer than 100 × 109/L, and significant bleeding occurs.
• B)protein C decreases significantly before full anticoagulation, and skin thrombosis results.
• C)prothrombin decreases rapidly generating less thrombin, and significant bleeding occurs.
• D)plasminogen increases, and rapid clot lysis occurs.

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