Which Description Is Consistent with Chronic Myelogenous Leukemia (CML)

question 8

Multiple Choice

Which description is consistent with chronic myelogenous leukemia (CML) ?

• A)Defects exist in the ras oncogene, TP53 tumor-suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein.
• B)Leukocytosis and a predominance of blast cells characterize the bone marrow and peripheral blood. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.
• C)B cells fail to mature into plasma cells that synthesize immunoglobulins.
• D)The translocation of genetic material from genes 9 and 22 creates an abnormal, fused protein identified as BCR-ABL1.

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Definitions:

Counterconditioning

A behavioral therapy technique where a negative or unwanted response to a stimulus is replaced with a positive one.

Adaptive Disclosure Treatment

A therapeutic approach designed for combat veterans that focuses on openly discussing combat experiences and moral injuries.

Cognitive Restructuring

A therapeutic process that aims to challenge and change unhealthy thought patterns to more rational, adaptive ones.

In Vivo Exposure

A therapeutic technique involving direct exposure to a feared object, situation, or activity in real-life conditions.