Match the Types of Cryoglobulin with the Correct Description $\kappa$ Light Chains

question 4

Multiple Choice

Match the types of cryoglobulin with the correct description.
-Type II

• A)Mixed cryoglobulins in which both constituent immunoglobulins are polyclonal. More than 90% contain IgM rheumatoid factor and IgG. These cryoglobulins are seen in a variety of autoimmune, systemic rheumatic diseases and persistent infections with immune complexes (e.g., bacterial endocarditis).
• B)Cryoglobulins composed of a single class; IgM and IgG classes most common; IgA or light-chain, single cryoglobulins seen less frequently. This type constitutes about 25% of cryoglobulins and is generally associated with multiple myeloma, macroglobulinemia, and other, rarer neoplastic proliferations of plasma cells and lymphocytes.
• C)Cryoglobulins consist of two forms. The monoclonal form always has rheumatoid factor activity and usually is an IgM with \(\kappa\) light chains. The second form is polyclonal IgG, which reacts with the monoclonal IgM rheumatoid factor.

---

Definitions:

Personal Construct System

A psychological framework suggesting individuals use personal constructs, which are unique, dichotomous concepts, to interpret and predict the world around them.

George Kelly

An American psychologist known for his development of personal construct psychology.

Interpersonal Circumplex

A model that categorizes and describes human interpersonal behaviors and personality traits along two dimensions: dominance and warmth.

Skills

The ability to do something well; expertise or competence in a particular activity or domain.