A New Drug Designed for the Treatment of Lung Cancer

question 48

Multiple Choice

A new drug designed for the treatment of lung cancer must specifically enter the cytoplasm of lung cells while not entering the cells of other tissues. Which of the following characteristics would likely enhance the specificity of this drug?

• A) the relative hydrophobicity of the drug molecule
• B) the phospholipid composition of lung cell membranes
• C) the specificity of the drug molecule for binding to the extracellular matrix of lung cells
• D) the similarity of the drug molecule to other molecules normally transported lung cells

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Definitions:

Concentration Ratio

A measure of the total output produced in an industry by a given number of firms, used to assess the level of market concentration and competition.

Corporate Concentration

The degree to which a small number of firms control a large market share of the total output or sales within an industry.

Herfindahl-Hirschman Index

A measure of market concentration to evaluate the competitive landscape, calculated by summing the squares of the market shares of all firms in the industry.

Herfindahl-Hirschman Index

A measure of market concentration and competition, calculated by squaring the market share of each firm competing in a market and summing the resulting numbers.