Tetrodotoxin Blocks Voltage-Gated Sodium Channels, and Ouabain Blocks Sodium-Potassium Pumps

question 4

Multiple Choice

Tetrodotoxin blocks voltage-gated sodium channels, and ouabain blocks sodium-potassium pumps. If you added both tetrodotoxin and ouabain to a solution containing neural tissue, what responses would you expect?

• A) immediate loss of resting potential
• B) immediate loss of action potential with gradual shift of resting potential
• C) slow decrease of resting potential and action potential amplitudes
• D) No effect; the substances counteract each other.

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