Use the following figure to answer the question. 
Which labeled structure is influenced by hormones to change the concentration of the urine?
Definitions:
Migraine
A neurological condition characterized by intense, debilitating headaches often accompanied by nausea and sensitivity to light or sound.
Indigestion
A condition resulting from the difficulty in digesting food, marked by discomfort or heartburn.
Perimenopausal
The transition phase before menopause, marked by changes in menstrual cycle and symptoms like hot flashes.
Estrogen
A group of steroid hormones that play a vital role in the development and functioning of female reproductive tissues, as well as secondary sexual characteristics.
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