A Microarray Is a Tool Used in Genetic Research to Determine

question 36

Multiple Choice

A microarray is a tool used in genetic research to determine the relative level of expression of mRNAs in a particular tissue. One use of the technology is in cancer diagnosis and treatment. Which of the following pieces of evidence would support diagnosis of a cancer due to a mutation in a tumor-suppressor gene?

• A) The tissue sample shows a high level of gene expression relative to a control (noncancerous) sample.
• B) The tissue sample responds to treatment with a mitosis-promoting compound.
• C) The mRNAs for the targeted tumor suppressor sequence are not being produced.
• D) The mRNAs for cyclins and kinases show unusually high levels of expression.

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