Rank the Following Mutations with Respect to Their Likelihood of Affecting

question 69

Multiple Choice

Rank the following mutations with respect to their likelihood of affecting the structure of the polypeptide (from most likely to affect structure to least likely) .
1) insertion mutation in the middle of an intron
2) deletion of 3 bases crossing an intron-exon border
3) substitution mutation at the third position of a codon
4) substitution mutation at the second position of a codon

• A) 1, 2, 4, 3
• B) 2, 3, 4, 1
• C) 3, 4, 2, 1
• D) 4, 3, 2, 1

---

Definitions:

Sunk Cost

Refers to money that has already been spent and cannot be recovered, which should not influence future business decisions.

Standard Cost Formula

A predetermined cost of manufacturing a single unit or a number of product units during a specific period under normal conditions, used for budgeting and cost control.

Total Cost

The aggregate amount of all costs involved in producing a product or delivering a service, including direct materials, labor, and overhead expenses.

Indirect Manufacturing Cost

Costs in manufacturing that are not directly traceable to individual products, such as maintenance, utilities, and factory supervision.