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We can try to map the surface of a globular protein in two dimensions just like we depict the surface of the Earth in a world map. On such a map, the binding site of a molecule for other molecules of the same protein (for assembly into a multisubunit complex) can be marked. In the following "maps," two molecules of the protein can bind if the points a, b, and c on the surface of one molecule can align to points a′, b′, and c′ in the other molecule, respectively. Which map corresponds to a protein whose assembly gives rise to a helix? Hint: the other maps correspond to a dimer, a ring, and a linear filament.
Professional Bureaucracy
An organizational structure where power is held by professionals with specialized knowledge rather than through formal managerial positions.
Standardization
The process of implementing and developing technical standards to ensure consistency, safety, and efficiency across products, services, and procedures.
Coordination
The organization of the different elements of a complex body or activity so as to enable them to work together effectively.
Machine Bureaucracy
A highly structured organizational form that operates through standardized procedures and a clear hierarchy of authority.
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