For a simple enzymatic reaction that involves only one substrate and follows Michaelis-Menten kinetics, the changes in the concentrations of substrate, product, free enzyme, and the enzyme-substrate complex over the course of the reaction are depicted by solid curves in the graph below. Which curve (1 to 4) corresponds to [ES]? Write down the number as your answer.
![For a simple enzymatic reaction that involves only one substrate and follows Michaelis-Menten kinetics, the changes in the concentrations of substrate, product, free enzyme, and the enzyme-substrate complex over the course of the reaction are depicted by solid curves in the graph below. Which curve (1 to 4) corresponds to [ES]? Write down the number as your answer.](https://d2lvgg3v3hfg70.cloudfront.net/TB1030/11ea33de_1b49_f77b_bddc_e7510d8256b9_TB1030_00.jpg)
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