The Results of Two Sets of Chromatin Immunoprecipitation Experiments on Two

question 84

Multiple Choice

The results of two sets of chromatin immunoprecipitation experiments on two cell types (1 and 2) are shown in the following simplified graphs for the same genomic region containing the first two exons of a gene. Antibodies against a transcription regulatory protein (X) or against a subunit of RNA polymerase II were used in the ChIP-seq experiments, as indicated. Do you think the protein is a transcriptional activator or repressor? The results from a parallel RNA-seq experiment are provided in the third graph. Which profile (a or b) in the graph would you expect to correspond to cell type 1?

• A) Activator; profile a
• B) Repressor; profile a
• C) Activator; profile b
• D) Repressor; profile b

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Definitions:

Accommodation

In cognitive development, the process of altering one's existing schemas or ideas as a result of new information or experiences.

Schema

A cognitive framework or concept that helps organize and interpret information, forming the basis of understanding experiences.

Secondary Circular Reactions

Secondary circular reactions are a developmental phase in infants, occurring around 4-8 months, characterized by the repetition of actions that produce effects outside the body, showing an early awareness of cause and effect.

Sensorimotor

The first stage in Piaget's theory of cognitive development, where infants learn through interacting with the environment, from birth to about 2 years of age.