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Electron Microscopy Samples Are Often Chemically Fixed Before Dehydration, Resin-Embedding

question 6

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Electron microscopy samples are often chemically fixed before dehydration, resin-embedding, and sectioning. But they can also be "fixed" by rapid freezing, in a way that precludes ice-crystal formation, to ensure minimal damage to the original cell structures. How can this be done?

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