Neuromuscular Transmission Involves the Sequential Activation of Several Ion Channels

question 35

Short Answer

Neuromuscular transmission involves the sequential activation of several ion channels. Sort the following events to reflect the sequence leading to muscle contraction. Your answer would be a five-digit number composed of numbers 1 to 5 only, e.g. 12543.
(A) Opening of voltage-gated Na? channels in the muscle cell plasma membrane.
(B) Opening of Ca²⁺ release channels in the sarcoplasmic reticulum membrane.
(C) Opening of ionotropic acetylcholine receptors on the muscle cell plasma membrane.
(D) Opening of voltage-gated Ca²⁺channels in the T tubules.
(E) Opening of voltage-gated Ca²⁺channels in the motor neuron.

---

Definitions:

Special Verdict

A verdict in a jury trial where the jury is asked to make findings on specific factual issues rather than simply deciding on the overall outcome.

Negotiation

The process of discussing something formally to reach an agreement or compromise between parties.

Conciliation

A process in dispute resolution where an impartial third party, the conciliator, assists the conflicting parties to reach a voluntary, amicable settlement.

Mediation

A form of alternative dispute resolution where a neutral third party helps disputing parties find a mutually satisfactory solution to their conflict.